👉 Tonight fluid, also known as nighttime interstitial fluid, is a transient state of increased interstitial fluid volume that occurs during sleep. This phenomenon is characterized by a temporary rise in the extracellular fluid space within tissues, particularly in areas like the brain and muscles, as a result of reduced blood flow and metabolic activity. This fluid accumulation is thought to play a role in clearing metabolic waste products, such as beta-amyloid and tau proteins, which are associated with neurodegenerative diseases like Alzheimer's. Despite its transient nature, nighttime fluid dynamics are crucial for maintaining tissue homeostasis and potentially influencing cognitive functions during sleep.